mouse ESPL1 shRNA silencing AAV

Cat. No: shAAV-258712

Availability: 4-5 weeks

Name: AAV-m-ESPL1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Espl1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Espl1
Gene Name: extra spindle pole bodies 1, separase
Gene ID: 105988
Gene Synonyms: AL024103; AU045071; Cerp; ESP1; PRCE; SSE
ORF Size: 6357 bp
RefSeq#: NM_001014976
Gene Description: Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.
UniGene ID: Mm.288324