mouse KALRN shRNA silencing AAV

Cat. No: shAAV-262557

Availability: 6-8 weeks

Name: AAV-m-KALRN-shRNA

This is an AAV expressing shRNA for silencing of Mouse Kalrn.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Kalrn
Gene Name: kalirin, RhoGEF kinase
Gene ID: 545156
Gene Synonyms: 2210407G14Rik; AV235988; DUET; E530005C20Rik; Gm539; Hapip; TRAD
ORF Size: 4965 bp
RefSeq#: NM_177357
Gene Description: Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity.
UniGene ID: Mm.450612