human SLC5A12 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SLC5A12

Gene Name

solute carrier family 5 member 12

Gene ID

159963

Gene Synonyms

SMCT2

ORF Size

1191 bp

RefSeq#

NM_178498

Gene Description

Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 (PubMed 17692818)).(supplied by OMIM, Dec 2008)

UniGene ID

Hs.148907

HGNC ID

HGNC:28750