human GRK4 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GRK4

Gene Name

G protein-coupled receptor kinase 4

Gene ID

2868

Gene Synonyms

GPRK2L; GPRK4; GRK4a; IT11

ORF Size

1737 bp

RefSeq#

NM_001004056

Gene Description

GRK4 encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. GRK4 has been linked to both genetic and acquired hypertension.

UniGene ID

Hs.32959

HGNC ID

HGNC:4543