mouse ESPL1 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Espl1

Gene Name

extra spindle pole bodies 1, separase

Gene ID

105988

Gene Synonyms

AL024103; AU045071; Cerp; ESP1; PRCE; SSE

ORF Size

6357 bp

RefSeq#

NM_001014976

Gene Description

Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.

UniGene ID

Mm.288324