human SLC5A12 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-223537
Availability:
3-5 weeks
Name:
AAV-h-SLC5A12
This is an AAV expressing Human SLC5A12.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SLC5A12
- Gene Name
- solute carrier family 5 member 12
- Gene ID
- 159963
- Gene Synonyms
- SMCT2
- ORF Size
- 1191 bp
- RefSeq#
- BC049207
- Gene Description
- Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 (PubMed 17692818)).(supplied by OMIM, Dec 2008)
- UniGene ID
- Hs.148907
- HGNC ID
- HGNC:28750
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