human RAB27A shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

RAB27A

Gene Name

RAB27A, member RAS oncogene family

Gene ID

5873

Gene Synonyms

GS2; HsT18676; RAB27; RAM

ORF Size

666 bp

RefSeq#

NM_004580

Gene Description

RAB27A belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

UniGene ID

Hs.654978

HGNC ID

HGNC:9766