mouse DOK1 Over-expression AAV

Cat. No: AAV-257383

Availability: 3-5 weeks

Name: AAV-m-DOK1

This is an AAV expressing Mouse Dok1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Dok1
Gene Name: docking protein 1
Gene ID: 13448
Gene Synonyms: AW557123; p62DOK
ORF Size: 1449 bp
RefSeq#: BC013066
Gene Description: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
UniGene ID: Mm.156