human RGS5 Over-expression AAV

Cat. No: AAV-221130

Availability: 3-5 weeks

Name: AAV-h-RGS5

This is an AAV expressing Human RGS5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RGS5
Gene Name: regulator of G-protein signaling 5
Gene ID: 8490
Gene Synonyms: MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129
ORF Size: 546 bp
RefSeq#: BC030059
Gene Description: RGS5 encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. RGS5 is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. RGS5 is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified.
UniGene ID: Hs.24950
HGNC ID: HGNC:10001