human GABRA1 Over-expression AAV

Cat. No: AAV-209506

Availability: 3-5 weeks

Name: AAV-h-GABRA1

This is an AAV expressing Human GABRA1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GABRA1
Gene Name: gamma-aminobutyric acid type A receptor alpha1 subunit
Gene ID: 2554
Gene Synonyms: ECA4; EIEE19; EJM; EJM5
ORF Size: 1371 bp
RefSeq#: BC030696
Gene Description: GABRA1 encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
UniGene ID: Hs.175934
HGNC ID: HGNC:4075