human PCBD1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PCBD1

Gene Name

pterin-4 alpha-carbinolamine dehydratase 1

Gene ID

5092

Gene Synonyms

DCOH; PCBD; PCD; PHS

ORF Size

315 bp

RefSeq#

NM_000281

Gene Description

PCBD1 encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1).

UniGene ID

Hs.3192

HGNC ID

HGNC:8646