human PCBD1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PCBD1.
shAAV-218304
AAV-h-PCBD1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PCBD1 (pterin-4 alpha-carbinolamine dehydratase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DCOH; PCBD; PCD; PHS
Description (Vector)
PCBD1 encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1).
Gene ID
5092
Gene Name (Vector)
pterin-4 alpha-carbinolamine dehydratase 1
Gene Symbol
PCBD1
HGNC ID
HGNC:8646
ORF Size (aa)
315
RefSeq ID
NM_000281
RefSeq Synonyms
NM_001323004, NM_001289797, NM_000281, BC006324,
Species
human
UniGene ID
Hs.3192
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.