human GSS Over-expression AAV

Cat. No: AAV-210591

Availability: 3-5 weeks

Name: AAV-h-GSS

This is an AAV expressing Human GSS.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GSS
Gene Name: glutathione synthetase
Gene ID: 2937
Gene Synonyms: GSHS; HEL-S-64p; HEL-S-88n
ORF Size: 1425 bp
RefSeq#: BC007927
Gene Description: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
UniGene ID: Hs.82327
HGNC ID: HGNC:4624