mouse RNF111 Over-expression AAV

Cat. No: AAV-281054

Availability: 3-5 weeks

Name: AAV-m-RNF111

This is an AAV expressing Mouse Rnf111.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rnf111
Gene Name: ring finger 111
Gene ID: 93836
Gene Synonyms: ARK; Arkadia
ORF Size: 2946 bp
RefSeq#: BC069835
Gene Description: Acts in the NODAL pathway of mesoderm patterning during embryonic development. Acts downstream AXIN1 as an E3 ubiquitin-protein ligase which promotes the ubiquitination of inhibitory SMADs such as SMAD7, induces their proteasomal degradation and thereby enhances the transcriptional activity of TGF-beta and BMP. Activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation.
UniGene ID: Mm.29783