human C1QB Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-203133
Availability:
3-5 weeks
Name:
AAV-h-C1QB
This is an AAV expressing Human C1QB.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- C1QB
- Gene Name
- complement C1q B chain
- Gene ID
- 713
- ORF Size
- 762 bp
- RefSeq#
- BC008983
- Gene Description
- C1QB encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QB encodes the B-chain polypeptide of human complement subcomponent C1q
- UniGene ID
- Hs.8986
- HGNC ID
- HGNC:1242
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