mouse DEF6 Over-expression AAV

Cat. No: AAV-256979

Availability: 3-5 weeks

Name: AAV-m-DEF6

This is an AAV expressing Mouse Def6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Def6
Gene Name: differentially expressed in FDCP 6
Gene ID: 23853
Gene Synonyms: 2410003F05Rik; 6430538D02Rik; AV094905; Ibp; Slat; Slat2; Slat6
ORF Size: 1893 bp
RefSeq#: BC131953
Gene Description: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling (By similarity).
UniGene ID: Mm.204731