mouse JMJD5 Over-expression AAV

Cat. No: AAV-262521

Availability: 3-5 weeks

Name: AAV-m-JMJD5

This is an AAV expressing Mouse Kdm8.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Kdm8
Gene Name: lysine (K)-specific demethylase 8
Gene ID: 77035
Gene Synonyms: 3110005O21Rik; Jmjd5
ORF Size: 1245 bp
RefSeq#: BC024807
Gene Description: Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.
UniGene ID: Mm.307239