mouse HSD17B10 Over-expression AAV

Cat. No: AAV-261695

Availability: 3-5 weeks

Name: AAV-m-HSD17B10

This is an AAV expressing Mouse Hsd17b10.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Hsd17b10
Gene Name: hydroxysteroid (17-beta) dehydrogenase 10
Gene ID: 15108
Gene Synonyms: 17bHSD10; Ads9; ERAB; Hadh2
ORF Size: 786 bp
RefSeq#: BC027517
Gene Description: Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
UniGene ID: Mm.6994