human KLF8 Over-expression AAV

Cat. No: AAV-213196

Availability: 3-5 weeks

Name: AAV-h-KLF8

This is an AAV expressing Human KLF8.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KLF8
Gene Name: Kruppel like factor 8
Gene ID: 11279
Gene Synonyms: BKLF3; ZNF741
ORF Size: 687 bp
RefSeq#: BC031355
Gene Description: KLF8 encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.646614
HGNC ID: HGNC:6351