human PPM1E Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-219578
Availability:
3-5 weeks
Name:
AAV-h-PPM1E
This is an AAV expressing Human PPM1E.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PPM1E
- Gene Name
- protein phosphatase, Mg2+/Mn2+ dependent 1E
- Gene ID
- 22843
- Gene Synonyms
- caMKN; CaMKP-N; POPX1; PP2CH
- ORF Size
- 2274 bp
- RefSeq#
- BC151228
- Gene Description
- PPM1E encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene.
- UniGene ID
- Hs.245044
- HGNC ID
- HGNC:19322
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