human PDGFRA Over-expression AAV

Cat. No: AAV-218508

Availability: 3-5 weeks

Name: AAV-h-PDGFRA

This is an AAV expressing Human PDGFRA.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PDGFRA
Gene Name: platelet derived growth factor receptor alpha
Gene ID: 5156
Gene Synonyms: CD140A; GAS9; PDGFR-2; PDGFR2; RHEPDGFRA
ORF Size: 2232 bp
RefSeq#: BC063414
Gene Description: PDGFRA encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
UniGene ID: Hs.74615
HGNC ID: HGNC:8803