human PDE8A Over-expression AAV

Cat. No: AAV-218495

Availability: 3-5 weeks

Name: AAV-h-PDE8A

This is an AAV expressing Human PDE8A.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PDE8A
Gene Name: phosphodiesterase 8A
Gene ID: 5151
Gene Synonyms: HsT19550
ORF Size: 2490 bp
RefSeq#: BC060762
Gene Description: PDE8A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.9333
HGNC ID: HGNC:8793