human MYD88 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-216145
Availability:
3-5 weeks
Name:
AAV-h-MYD88
This is an AAV expressing Human MYD88.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- MYD88
- Gene Name
- myeloid differentiation primary response 88
- Gene ID
- 4615
- Gene Synonyms
- MYD88D
- ORF Size
- 891 bp
- RefSeq#
- BC013589
- Gene Description
- MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
- UniGene ID
- Hs.82116
- HGNC ID
- HGNC:7562
Related Products
Control Products
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