human MMAB Over-expression AAV

Cat. No: AAV-215549

Availability: 3-5 weeks

Name: AAV-h-MMAB

This is an AAV expressing Human MMAB.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MMAB
Gene Name: methylmalonic aciduria (cobalamin deficiency) cblB type
Gene ID: 326625
Gene Synonyms: ATR; cblB; CFAP23; cob
ORF Size: 753 bp
RefSeq#: BC005054
Gene Description: MMAB encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. Alternatively spliced transcript variants have been found.
UniGene ID: Hs.12106
HGNC ID: HGNC:19331