human DST shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-233652
Availability:
5-8 weeks
Name:
Ad-h-DST-shRNA
This is an Adenovirus expressing shRNA for silencing of Human DST.
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Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- DST
- Gene Name
- dystonin
- Gene ID
- 667
- Gene Synonyms
- BP240; BPA; BPAG1; CATX-15; CATX15; D6S1101; DMH; DT; EBSB2; HSAN6; MACF2
- ORF Size
- 3432 bp
- RefSeq#
- NM_001723
- Gene Description
- DST encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been reported that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.
- HGNC ID
- HGNC:1090
Related Products
Product | Cat No. |
---|---|
AAV-h-DST | AAV-233652 |
Ad-h-DST | ADV-233652 |
AAV-h-DST-shRNA | shAAV-233652 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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