human FANCA shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-230923
Availability:
3-5 weeks
Name:
Ad-h-FANCA-shRNA
This is an Adenovirus expressing shRNA for silencing of Human FANCA.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- FANCA
- Gene Name
- Fanconi anemia complementation group A
- Gene ID
- 2175
- Gene Synonyms
- FA; FA-H; FA1; FAA; FACA; FAH; FANCH
- ORF Size
- 4368 bp
- RefSeq#
- NM_000135
- Gene Description
- The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.
- UniGene ID
- Hs.719210
- HGNC ID
- HGNC:3582
Related Products
Product | Cat No. |
---|---|
Ad-h-FANCA | ADV-229095 |
Ad-h-FANCA | ADV-230923 |
Ad-m-FANCA | ADV-259145 |
AAV-h-FANCA-shRNA | shAAV-230923 |
AAV-m-FANCA-shRNA | shAAV-259145 |
Ad-m-FANCA-shRNA | shADV-259145 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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