human SF3B3 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-230758
Availability:
3-5 weeks
Name:
Ad-h-SF3B3-shRNA
This is an Adenovirus expressing shRNA for silencing of Human SF3B3.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SF3B3
- Gene Name
- splicing factor 3b subunit 3
- Gene ID
- 23450
- Gene Synonyms
- RSE1; SAP130; SF3b130; STAF130
- ORF Size
- 3654 bp
- RefSeq#
- NM_012426
- Gene Description
- SF3B3 encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
- UniGene ID
- Hs.514435
- HGNC ID
- HGNC:10770
Related Products
Product | Cat No. |
---|---|
Ad-h-SF3B3 | ADV-230758 |
Ad-m-SF3B3 | ADV-271783 |
AAV-h-SF3B3-shRNA | shAAV-230758 |
AAV-m-SF3B3-shRNA | shAAV-271783 |
Ad-m-SF3B3-shRNA | shADV-271783 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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