human RPL8 shRNA silencing Adenovirus

Name 
Ad-h-RPL8-shRNA
Cat No 
shADV-221753
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RPL8.

shADV-221753
Ad-h-RPL8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RPL8 (ribosomal protein L8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
60S ribosomal protein L8; L8; large ribosomal subunit protein uL2
Description (eCommerce)
The gene RPL8 encodes 60S ribosomal protein L8 that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins and is located in the cytoplasm. In rat, the protein associates with the 5. 8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface [taken from NCBI Entrez Gene (Gene ID: 6132)].
Description (Vector)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein associates with the 5.8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface. Alternatively spliced transcript variants encoding the same protein exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Gene ID
6132
Gene Name (eCommerce)
ribosomal protein L8
Gene Name (Vector)
ribosomal protein L8
Gene Symbol
RPL8
HGNC ID
HGNC:10368
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
774
Protein Name (eCommerce)
60S ribosomal protein L8
RefSeq ID
NM_000973
RefSeq Synonyms
NM_033301, NM_001317782, NM_001317771, NM_000973, BC093064, BC013104, BC012197, BC000077,
Research Areas
Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,RNA Binding,RNA Processing,Signal Transduction,TNF Signaling,Translational Control
Research Areas (Faceted)
cell_biology,genetics,infectious_disease,metabolism,signal_transduction,transcription_translation
Species
human
Target Sentence
The gene RPL8 encodes 60S ribosomal protein L8 that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins and is located in the cytoplasm. In rat, the protein associates with the 5. 8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface [taken from NCBI Entrez Gene (Gene ID: 6132)].
UniGene ID
Hs.178551
UniProt ID (eCommerce)
P62917

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.