human ROD1 shRNA silencing Adenovirus

Name
Ad-h-ROD1-shRNA

Cat No
shADV-221477

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PTBP3.

shADV-221477

Ad-h-ROD1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PTBP3 (polypyrimidine tract binding protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

fission yeast differentiation regulator; polypyrimidine tract-binding protein 3; regulator of differentiation 1; ROD1; ROD1 regulator of differentiation 1

Description (eCommerce)

The protein encoded by the PTBP3 gene, polypyrimidine tract-binding protein 3, binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro [taken from NCBI Entrez Gene (Gene ID: 9991)].

Description (Vector)

PTBP3 binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene.

Gene ID

9991

Gene Name (eCommerce)

polypyrimidine tract binding protein 3

Gene Name (Vector)

polypyrimidine tract binding protein 3

Gene Symbol

PTBP3

HGNC ID

HGNC:10253

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1677

ORF Size (bp)

1677 bp

Protein Name (eCommerce)

Polypyrimidine tract-binding protein 3

RefSeq ID

NM_005156

RefSeq Synonyms

NM_005156, NM_001244898, NM_001244897, NM_001244896, NM_001163790, NM_001163788, BC044585,

Research Areas

mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing

Research Areas (Faceted)

cell_biology,genetics,transcription_translation

Species

human

Target Sentence

The protein encoded by the PTBP3 gene, polypyrimidine tract-binding protein 3, binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro [taken from NCBI Entrez Gene (Gene ID: 9991)].

UniGene ID

Hs.269988

UniProt ID (eCommerce)

O95758

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.