human PTPRA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTPRA.
shADV-220331
Ad-h-PTPRA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTPRA (protein tyrosine phosphatase, receptor type A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HEPTP; HLPR; HPTPA; HPTPalpha; LRP; PTPA; PTPRL2; R-PTP-alpha; RPTPA
Description (Vector)
PTPRA is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.
Gene ID
5786
Gene Name (Vector)
protein tyrosine phosphatase, receptor type A
Gene Symbol
PTPRA
HGNC ID
HGNC:9664
ORF Size (aa)
2382
ORF Size (bp)
2382 bp
RefSeq ID
NM_002836
RefSeq Synonyms
NM_080841, NM_080840, NM_002836, BC027308,
Species
human
UniGene ID
Hs.269577
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.