human PTHLH shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTHLH.
shADV-220268
Ad-h-PTHLH-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTHLH (parathyroid hormone like hormone). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BDE2; HHM; PLP; PTHR; PTHRP
Description (Vector)
PTHLH is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone.
Gene ID
5744
Gene Name (Vector)
parathyroid hormone like hormone
Gene Symbol
PTHLH
HGNC ID
HGNC:9607
ORF Size (aa)
528
RefSeq ID
NM_002820
RefSeq Synonyms
NM_198966, NM_198965, NM_198964, NM_002820, BC005961,
Species
human
UniGene ID
Hs.591159
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.