human PBRM1 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PBRM1

Gene Name

polybromo 1

Gene ID

55193

Gene Synonyms

BAF180; PB1

ORF Size

4959 bp

RefSeq#

NM_018165

Gene Description

This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma.

UniGene ID

Hs.476320

HGNC ID

HGNC:30064