human IMPAD1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

IMPAD1

Gene Name

inositol monophosphatase domain containing 1

Gene ID

54928

Gene Synonyms

GPAPP; IMP 3; IMP-3; IMPA3

ORF Size

1080 bp

RefSeq#

NM_017813

Gene Description

IMPAD1 encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1.

UniGene ID

Hs.716471

HGNC ID

HGNC:26019