human GUCY1B3 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GUCY1B3

Gene Name

guanylate cyclase 1 soluble subunit beta

Gene ID

2983

Gene Synonyms

GC-S-beta-1; GC-SB3; GUC1B3; GUCB3; GUCSB3; GUCY1B1

ORF Size

1860 bp

RefSeq#

NM_000857

Gene Description

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit and a beta subunit, typically GUCY1B3, catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide (NO) and nitrovasodilator drugs (Zabel et al., 1998 (PubMed 9742212)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.77890

HGNC ID

HGNC:4687