human GLI2 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-209966
Availability:
Immediate
Name:
Ad-h-GLI2-shRNA
This is an Adenovirus expressing shRNA for silencing of Human GLI2.
Request a Quote
Please enter your email address and we'll be in touch with more information:
Product Info
- Knockdown
- >60% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GLI2
- Gene Name
- GLI family zinc finger 2
- Gene ID
- 2736
- Gene Synonyms
- CJS; HPE9; PHS2; THP1; THP2
- ORF Size
- 4761 bp
- RefSeq#
- NM_005270
- Gene Description
- GLI2 encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.
- UniGene ID
- Hs.111867
- HGNC ID
- HGNC:4318
Related Products
Product | Cat No. |
---|---|
Ad-h-GLI2 | ADV-209966 |
Ad-m-GLI2 | ADV-260173 |
Ad-m-GLI2 | ADV-260174 |
AAV-h-GLI2-shRNA | shAAV-209966 |
AAV-m-GLI2-shRNA | shAAV-260173 |
Ad-m-GLI2-shRNA | shADV-260173 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
Toll-free (US Only): 877-BIO-LABS
Fax: +1 215-525-1112
Privacy Policy