human EIF3D shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human EIF3D.
shADV-207738
Ad-h-EIF3D-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human EIF3D (eukaryotic translation initiation factor 3 subunit D). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
eIF3 p66; eIF3d; eIF3-p66; EIF3S7; eIF-3-zeta; eIF3-zeta; Eukaryotic translation initiation factor 3 subunit 7; eukaryotic translation initiation factor 3 subunit D; eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa; translation initiation factor eIF3 p66 subunit
Description (eCommerce)
Eukaryotic initiation factor 3 subunit D (eIF3D) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5’-end of cellular mRNAs near the cap structure (m7GpppN).
Description (Vector)
Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex.
Gene ID
8664
Gene Name (eCommerce)
eukaryotic translation initiation factor 3 subunit D
Gene Name (Vector)
eukaryotic translation initiation factor 3 subunit D
Gene Symbol
EIF3D
HGNC ID
HGNC:3278
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1647
ORF Size (bp)
1647 bp
Protein Name (eCommerce)
Eukaryotic translation initiation factor 3 subunit D
RefSeq ID
NM_003753
RefSeq Synonyms
NM_003753, BC101477, BC093686, BC093100, BC080515, BC014912, BC000469, BC000328,
Research Areas
Gene Expression,Metabolism/Metabolic Process,mRNA Binding,RNA Transport,Translational Control
Research Areas (Faceted)
genetics,transcription_translation,metabolism,cell_biology
Species
human
Target Sentence
Eukaryotic initiation factor 3 subunit D (eIF3D) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5’-end of cellular mRNAs near the cap structure (m7GpppN).
UniGene ID
Hs.55682
UniProt ID (eCommerce)
O15371
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.