human EHMT1 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-207688
Availability:
Immediate
Name:
Ad-h-EHMT1-shRNA
This is an Adenovirus expressing shRNA for silencing of Human EHMT1.
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Product Info
- Knockdown
- >70% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- EHMT1
- Gene Name
- euchromatic histone lysine methyltransferase 1
- Gene ID
- 79813
- Gene Synonyms
- bA188C12.1; Eu-HMTase1; EUHMTASE1; FP13812; GLP; GLP1; KMT1D
- ORF Size
- 2427 bp
- RefSeq#
- NM_024757
- Gene Description
- EHMT1 is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome). Two transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.495511
- HGNC ID
- HGNC:24650
Related Products
Product | Cat No. |
---|---|
AAV-h-EHMT1 | AAV-207688 |
Ad-h-EHMT1 | ADV-207688 |
AAV-h-EHMT1-shRNA | shAAV-207688 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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