human DSN1 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

DSN1

Gene Name

DSN1 homolog, MIS12 kinetochore complex component

Gene ID

79980

Gene Synonyms

C20orf172; dJ469A13.2; hKNL-3; KNL3; MIS13

ORF Size

1071 bp

RefSeq#

NM_024918

Gene Description

DSN1 encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants.

UniGene ID

Hs.632268

HGNC ID

HGNC:16165