rat FNTA shRNA silencing AAV

Cat. No: shAAV-292163

Availability: 4-5 weeks

Name: AAV-r-FNTA-shRNA

This is an AAV expressing shRNA for silencing of Rat Fnta.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Fnta
Gene Name: farnesyltransferase, CAAX box, alpha
Gene ID: 25318
Gene Synonyms: PFAS
ORF Size: 1134 bp
RefSeq#: NM_012847
Gene Description: Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK (By similarity).