mouse UHRF2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Uhrf2.
shAAV-275613
AAV-m-UHRF2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Uhrf2 (ubiquitin-like, containing PHD and RING finger domains 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310065A22Rik; AI426270; AW214556; D130071B19Rik; Nirf
Description (Vector)
E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. Appears to contribute to tumorigenesis.
Gene ID
109113
Gene Name (Vector)
ubiquitin-like, containing PHD and RING finger domains 2
Gene Symbol
Uhrf2
ORF Size (aa)
2412
ORF Size (bp)
2412 bp
RefSeq ID
NM_144873
RefSeq Synonyms
NM_144873, BC060241,
Species
mouse
UniGene ID
Mm.313364
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.