mouse SCN1B shRNA silencing AAV

Cat. No: shAAV-271443

Availability: 4-5 weeks

Name: AAV-m-SCN1B-shRNA

This is an AAV expressing shRNA for silencing of Mouse Scn1b.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Scn1b
Gene Name: sodium channel, voltage-gated, type I, beta
Gene ID: 20266
ORF Size: 657 bp
RefSeq#: NM_011322
Gene Description: Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons|Function: Isoform 2: Cell adhesion molecule that plays a critical role in neuronal migration and pathfinding during brain development. Stimulates neurite outgrowth.
UniGene ID: Mm.1418