mouse RBM5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rbm5.
shAAV-270268
AAV-m-RBM5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rbm5 (RNA binding motif protein 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D030069N10Rik
Description (Vector)
Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
Gene ID
83486
Gene Name (Vector)
RNA binding motif protein 5
Gene Symbol
Rbm5
ORF Size (aa)
2448
ORF Size (bp)
2448 bp
RefSeq ID
NM_148930
RefSeq Synonyms
NM_148930, BC054729, BC043058, BC031899, BC023854,
Species
mouse
UniGene ID
Mm.259197
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.