mouse PTRF shRNA silencing AAV

Name 
AAV-m-PTRF-shRNA
Cat No 
shAAV-269840
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ptrf.

shAAV-269840
AAV-m-PTRF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ptrf (polymerase I and transcript release factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310075E07Rik; AW546441; Cav-p60; Cavin
Description (Vector)
Plays an important role in caveolae formation and organization. Required for the sequestration of mobile caveolin into immobile caveolae. Termination of transcription by RNA polymerase I involves pausing of transcription by TTF1, and the dissociation of the transcription complex, releasing pre-rRNA and RNA polymerase I from the template. PTRF is required for dissociation of the ternary transcription complex.
Gene ID
19285
Gene Name (Vector)
polymerase I and transcript release factor
Gene Symbol
Ptrf
ORF Size (aa)
1179
ORF Size (bp)
1179 bp
RefSeq ID
NM_008986
RefSeq Synonyms
NM_008986, BC117527, BC116701, BC110698,
Species
mouse
UniGene ID
Mm.21864

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.