mouse KAT2A shRNA silencing AAV

Cat. No: shAAV-262567

Availability: 4-5 weeks

Name: AAV-m-KAT2A-shRNA

This is an AAV expressing shRNA for silencing of Mouse Kat2a.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Kat2a
Gene Name: K(lysine) acetyltransferase 2A
Gene ID: 14534
Gene Synonyms: 1110051E14Rik; AW212720; Gcn5; Gcn5l2; mmGCN5
ORF Size: 2490 bp
RefSeq#: NM_020004
Gene Description: Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
UniGene ID: Mm.218837