mouse IGSF8 shRNA silencing AAV

Cat. No: shAAV-262057

Availability: 4-5 weeks

Name: AAV-m-IGSF8-shRNA

This is an AAV expressing shRNA for silencing of Mouse Igsf8.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Igsf8
Gene Name: immunoglobulin superfamily, member 8
Gene ID: 140559
Gene Synonyms: ESTM34; EWI-2; KCT-4; PGRL
ORF Size: 1836 bp
RefSeq#: NM_080419
Gene Description: IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
UniGene ID: Mm.271717