mouse HDAC7 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-261180
Availability:
Immediate
Name:
AAV-m-HDAC7-shRNA
This is an AAV expressing shRNA for silencing of Mouse Hdac7.
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Product Info
- Knockdown
- >50% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Hdac7
- Gene Name
- histone deacetylase 7
- Gene ID
- 56233
- Gene Synonyms
- 5830434K02Rik; HD7; HD7a; Hdac7a; mFLJ00062
- ORF Size
- 2817 bp
- RefSeq#
- NM_019572
- Gene Description
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene.
- UniGene ID
- Mm.384027
Related Products
Product | Cat No. |
---|---|
AAV-h-HDAC7 | AAV-210893 |
AAV-m-HDAC7 | AAV-261180 |
Ad-h-HDAC7 | ADV-210893 |
Ad-m-HDAC7 | ADV-261180 |
AAV-h-HDAC7-shRNA | shAAV-210893 |
Ad-h-HDAC7-shRNA | shADV-210893 |
Ad-m-HDAC7-shRNA | shADV-261180 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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