mouse DTX4 shRNA silencing AAV

Cat. No: shAAV-257505

Availability: 4-5 weeks

Name: AAV-m-DTX4-shRNA

This is an AAV expressing shRNA for silencing of Mouse Dtx4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Dtx4
Gene Name: deltex 4, E3 ubiquitin ligase
Gene ID: 207521
Gene Synonyms: AI449438; BC044798; D930042H13; RNF155
ORF Size: 1851 bp
RefSeq#: NM_172442
Gene Description: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
UniGene ID: Mm.477187