mouse XRN1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-251610
Availability:
4-5 weeks
Name:
AAV-m-XRN1-shRNA
This is an AAV expressing shRNA for silencing of Mouse Xrn1.
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Product Info
- Knockdown
- >70% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Xrn1
- Gene Name
- 5'-3' exoribonuclease 1
- Gene ID
- 24127
- Gene Synonyms
- Dhm2; exo; mXrn1
- ORF Size
- 5172 bp
- RefSeq#
- NM_011916
- Gene Description
- Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
- UniGene ID
- Mm.291179
Related Products
Product | Cat No. |
---|---|
Ad-h-XRN1 | ADV-227937 |
Ad-m-XRN1 | ADV-251609 |
Ad-m-XRN1 | ADV-251610 |
AAV-h-XRN1-shRNA | shAAV-227937 |
Ad-h-XRN1-shRNA | shADV-227937 |
Ad-m-XRN1-shRNA | shADV-251610 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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