human ABCA1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-231712
Availability:
4-5 weeks
Name:
AAV-h-ABCA1-shRNA
This is an AAV expressing shRNA for silencing of Human ABCA1.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ABCA1
- Gene Name
- ATP binding cassette subfamily A member 1
- Gene ID
- 19
- Gene Synonyms
- ABC-1; ABC1; CERP; HDLDT1; TGD
- ORF Size
- 6786 bp
- RefSeq#
- NM_005502
- Gene Description
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
- UniGene ID
- Hs.719214
- HGNC ID
- HGNC:29
Related Products
Product | Cat No. |
---|---|
Ad-h-ABCA1 | ADV-231712 |
Ad-m-ABCA1 | ADV-251753 |
Ad-m-ABCA1 | ADV-251754 |
AAV-m-ABCA1-shRNA | shAAV-251754 |
Ad-h-ABCA1-shRNA | shADV-231712 |
Ad-m-ABCA1-shRNA | shADV-251754 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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