human USP5 shRNA silencing AAV

Cat. No: shAAV-227340

Availability: 4-5 weeks

Name: AAV-h-USP5-shRNA

This is an AAV expressing shRNA for silencing of Human USP5.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: USP5
Gene Name: ubiquitin specific peptidase 5
Gene ID: 8078
Gene Synonyms: ISOT
ORF Size: 2508 bp
RefSeq#: NM_003481
Gene Description: Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 (PubMed 7578059)).(supplied by OMIM, Mar 2010)
UniGene ID: Hs.631661
HGNC ID: HGNC:12628